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Statins, Fat, and the Prostate

By Dr. Jerry Mixon December 7, 2009

A recent study of prostate cancer, funded by the federal government, linked high cholesterol levels with doubling the risk of developing an aggressive cancer that is more likely to result in death. The study, which involved over 6000 men, showed there was a clear correlation between a cholesterol level over 200 and a doubling in the incidence of high-grade malignancies of the prostate. As a result, some have leapt to the conclusion that placing men on statin drugs, which are a class of drugs that lower cholesterol levels, should lower the risk of prostate cancer (or at least lower the risk of high-grade aggressive prostate cancer).

I wish life was that straight forward, but the data on statin use and prostate cancer incidence is complex. There are studies indicating that long-term use of statin drugs may decrease the overall risk of prostate cancer to some modest degree. On the other hand, a large study, published in September of 2009 and done here at the Seattle Fred

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